{"id":2006,"date":"2024-02-01T00:00:25","date_gmt":"2024-02-01T05:00:25","guid":{"rendered":"https:\/\/www.centre-stopad.com\/?p=2006"},"modified":"2024-05-08T17:30:28","modified_gmt":"2024-05-08T21:30:28","slug":"midlife-physical-activity-engagement-is-associated-with-later-life-brain-health-ai-m-et-al-2023","status":"publish","type":"post","link":"https:\/\/www.centre-stopad.com\/en\/2024\/02\/01\/midlife-physical-activity-engagement-is-associated-with-later-life-brain-health-ai-m-et-al-2023\/","title":{"rendered":"Midlife physical activity engagement is associated with later-life brain health. (Ai M. et al., 2024)"},"content":{"rendered":"<div class=\"wp-block-stackable-columns stk-block-columns stk-block stk-f68af85\" data-block-id=\"f68af85\"><style>.stk-f68af85-column{--stk-columns-spacing:12px !important;--stk-column-gap:12px !important}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-f68af85-column\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-0bb6bd7\" data-v=\"4\" data-block-id=\"0bb6bd7\"><style>@media screen and (min-width:768px){.stk-0bb6bd7{flex:1 1 calc(25% - var(--stk-column-gap,0px) * 1 \/ 2 ) !important}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-0bb6bd7-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-0bb6bd7-inner-blocks\">\n<div class=\"wp-block-stackable-image stk-block-image stk-block stk-3a7774a\" data-block-id=\"3a7774a\"><figure><span class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-2008\" src=\"https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h.jpeg\" width=\"576\" height=\"768\" srcset=\"https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h.jpeg 576w, https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h-225x300.jpeg 225w, https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h-9x12.jpeg 9w\" sizes=\"auto, (max-width: 576px) 100vw, 576px\" \/><\/span><\/figure><\/div>\n\n\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-fc0d2be\" data-block-id=\"fc0d2be\"><style>.stk-fc0d2be .stk-block-text__text{font-size:12px !important}@media screen and (max-width:1023px){.stk-fc0d2be .stk-block-text__text{font-size:12px !important}}<\/style><p class=\"stk-block-text__text\"><span style=\"color: #abb8c3;\" class=\"stk-highlight\"><strong>Citation : <\/strong><br>Ai, M., Morris, T. P., Noriega de la Colina, A., Thovinakere, N., Tremblay-Mercier, J., Villeneuve, S., H Hillman, C., Kramer, A. F., Geddes, M. R., &amp; PREVENT-AD Research Group (2024). Midlife physical activity engagement is associated with later-life brain health.&nbsp;<em>Neurobiology of aging<\/em>,&nbsp;<em>134<\/em>, 146\u2013159. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2023.11.004<\/span><\/p><\/div>\n\n\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-0055278\" data-block-id=\"0055278\"><style>.stk-0055278 .stk-block-text__text{font-size:12px !important}@media screen and (max-width:1023px){.stk-0055278 .stk-block-text__text{font-size:12px !important}}<\/style><p class=\"stk-block-text__text\"><span style=\"color: #0693e3;\" class=\"stk-highlight\">Full text : <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0197458023002580?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">Here<\/a><\/p><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-36f0c6d\" data-v=\"4\" data-block-id=\"36f0c6d\"><style>@media screen and (min-width:768px){.stk-36f0c6d{flex:1 1 calc(75% - var(--stk-column-gap,0px) * 1 \/ 2 ) !important}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-36f0c6d-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-36f0c6d-inner-blocks\">\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-4b1e40a\" id=\"a-href-https-www-sciencedirect-com-science-article-pii-s-0197458023002580-via-3-dihub-target-blank-rel-noreferrer-noopener-midlife-physical-activity-engagement-is-associated-with-later-life-brain-health-a\" data-block-id=\"4b1e40a\"><h2 class=\"stk-block-heading__text\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0197458023002580?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">Midlife physical activity engagement is associated with later-life brain health.<\/a><\/h2><\/div>\n\n\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-c5ea493\" data-block-id=\"c5ea493\"><p class=\"stk-block-text__text has-text-align-justify\"><strong>Samson AD, Rajagopal S, Pasvanis S, Villeneuve S; PREVENT-AD Research Group; McIntosh AR, Rajah MN.<br><\/strong><br>published in <em>Neurobiology of Aging<\/em> , February 2024. <\/p><\/div>\n\n\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-b6385a4\" data-block-id=\"b6385a4\"><style>.stk-b6385a4 .stk-block-text__text{font-size:12px !important}@media screen and (max-width:1023px){.stk-b6385a4 .stk-block-text__text{font-size:12px !important}}<\/style><p class=\"stk-block-text__text has-text-align-justify\"><strong>ABSTRACT<\/strong> <strong>:<\/strong><br>The relationship between midlife&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/psychology\/physical-activity\">physical activity<\/a>&nbsp;(PA), and cognition and brain health in later life is poorly understood with conflicting results from previous research. Investigating the contribution of midlife PA to later-life cognition and brain health in high-risk populations will propel the development of health guidance for those most in need. The current study examined the association between midlife PA engagement and later-life cognition, grey matter characteristics and resting-state&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/functional-connectivity\">functional connectivity<\/a>&nbsp;in older individuals at high-risk for Alzheimer\u2019s disease. The association between midlife PA and later-life cognitive function was not significant but was moderated by later-life PA. Meanwhile, greater midlife moderate-to-vigorous PA was associated with greater grey matter&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/biochemistry-genetics-and-molecular-biology\/surface-area\">surface area<\/a>&nbsp;in the left&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/middle-frontal-gyrus\">middle frontal gyrus<\/a>. Moreover, greater midlife total PA was associated with diminished&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/functional-connectivity\">functional connectivity<\/a>&nbsp;between bilateral middle frontal gyri and middle&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/cingulum\">cingulum<\/a>,&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/supplementary-motor-area\">supplementary motor areas<\/a>, and greater&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/psychology\/functional-connectivity\">functional connectivity<\/a>&nbsp;between bilateral&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/hippocampus\">hippocampi<\/a>&nbsp;and right&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/cerebellum\">cerebellum<\/a>, Crus II. These results indicate the potentially independent contribution of midlife PA to later-life brain health.<br><br><\/p><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Citation : Ai, M., Morris, T. P., Noriega de la Colina, A., Thovinakere, N., Tremblay-Mercier, J., Villeneuve, S., H Hillman, C., Kramer, A. F., Geddes, M. R., &amp; PREVENT-AD Research Group (2024). Midlife physical activity engagement is associated with later-life brain health.&nbsp;Neurobiology of aging,&nbsp;134, 146\u2013159. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2023.11.004 Full text : Here Midlife physical activity engagement is [&hellip;]<\/p>","protected":false},"author":2,"featured_media":2008,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[11,9],"tags":[15],"class_list":["post-2006","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-11","category-publication-scientifique","tag-publications-scientifiques"],"uagb_featured_image_src":{"full":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h.jpeg",576,768,false],"thumbnail":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h-150x150.jpeg",150,150,true],"medium":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h-225x300.jpeg",225,300,true],"medium_large":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h.jpeg",576,768,false],"large":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h.jpeg",576,768,false],"1536x1536":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h.jpeg",576,768,false],"2048x2048":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h.jpeg",576,768,false],"trp-custom-language-flag":["https:\/\/www.centre-stopad.com\/wp-content\/uploads\/2024\/03\/1-s2.0-S0197458023X0013X-cov200h-9x12.jpeg",9,12,true]},"uagb_author_info":{"display_name":"Jennifer Tremblay-Mercier","author_link":"https:\/\/www.centre-stopad.com\/en\/author\/jennifer-tremblay-mercier\/"},"uagb_comment_info":0,"uagb_excerpt":"Citation : Ai, M., Morris, T. P., Noriega de la Colina, A., Thovinakere, N., Tremblay-Mercier, J., Villeneuve, S., H Hillman, C., Kramer, A. F., Geddes, M. R., &amp; PREVENT-AD Research Group (2024). Midlife physical activity engagement is associated with later-life brain health.&nbsp;Neurobiology of aging,&nbsp;134, 146\u2013159. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2023.11.004 Full text : Here Midlife physical activity engagement is&hellip;","_links":{"self":[{"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/posts\/2006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/comments?post=2006"}],"version-history":[{"count":4,"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/posts\/2006\/revisions"}],"predecessor-version":[{"id":2203,"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/posts\/2006\/revisions\/2203"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/media\/2008"}],"wp:attachment":[{"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/media?parent=2006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/categories?post=2006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.centre-stopad.com\/en\/wp-json\/wp\/v2\/tags?post=2006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}